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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of retinoblastoma (RB)
ncRNA name PlncRNA-1
ncRNA Category lncRNA
ID 100506428
Ensembl ENSG00000236830
Synonyms CBR3-AS1
Disease name retinoblastoma (RB)
Species Homo sapiens
Tissues/Cell_line RB samples, normal retinas; RB cell lines Y79, WERI-RB1;RPE cell line ARPE-19; human retinal microvascular endothelial cells (HRMECs)
Methods qPCR, transfection, Western blot, CCK-8 assay, transwell assay
Expression pattern up-regulated
Functional description PlncRNA-1 serves as an oncogenic lncRNA in regulating retinoblastoma cell proliferation, migration, and invasion through proliferation, migration, and invasion through up-regulating CBR3.
PubMed ID 30096220
Year 2018
Title PlncRNA-1 is overexpressed in retinoblastoma and regulates retinoblastoma cell proliferation and motility through modulating CBR3.
Drug-related ncRNA NO

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